After install go fo /opt/RepeatMasker and run the RepeatMasker Configuration Program: # perl ./configure Paths are as follows: **PERL PROGRAM** /usr/bin/perl **REPEATMASKER INSTALLATION DIRECTORY** /opt/RepeatMasker **TRF PROGRAM** /usr/bin/trf Add a Search Engine: 1. CrossMatch: you should obtain this yourself, with the proper license, following the instructions here http://www.phrap.org/ 2. RMBlast - NCBI Blast with RepeatMasker extensions: this is available from SBo. 3. WUBlast/ABBlast (required by DupMasker): you should obtain this yourself, with the proper license, following the instructions here https://blast.advbiocomp.com/licensing/ 4. HMMER3.1 & DFAM: this is available from SBo. **RMBlast (rmblastn) INSTALLATION PATH** /usr/bin **HMMER INSTALLATION PATH** /usr/bin